Ongoing Collaborative Projects
RNA standards
Collect existing standards and synthesize the remaining standards.
Ensure that standards are available for technology development and eventually therapeutics.
Develop technologies for sequencing full-length RNA with all modifications
Develop technologies that can identify all 150+ modifications, obtain sequences with high accuracy cheaply without needing large amount of RNA.
Establish data standards for direct RNA sequencing methods
Develop algorithms to analyze Nanopore and mass spectrometry data; and ones for new sequencing methods.
Databases for direct RNA sequencing data
Expand existing databases such as Modomics by setting one-letter code for all modifications, house sequencing data and display them in a user-friendly manner.
Sequence RNA of two human cell lines
Establish protocols for extracting RNAs, assessing RNA quality, and sequencing them to assess the technological gaps.
Outreach & workforce development
Discuss with the public the importance of the Human RNome Project, and why studying RNA is important. Develop a workforce with expertise in all aspects of RNA.